Synthesis, Characterization and Biological Screening of 3,3- Diethyl Benzoylthiourea derivatives

Abstract

Synthesis, characterization and Antimicrobial Activity of some 3,3-diethyl benzoylthiourea derivatives have been described and tested for in vitro antibacterial activity against Proteus mirabilis, Escherichia coli (gram negative). Bacillus subtilis, Staphylococcus aureus (gram positive) bacteria and in vitro antifungal activity against Candida parapsilosis and Candida albicans by employing agar and potato dextrose agar, respectively, using a paper disc method. The results reveal that the compounds exhibited moderate antibacterial and antifungal activities. The standard antibiotics have been used to compare the results. However, the structural of synthesized compounds were confirmed by spectral data.