Effect Indol acetic acid On liver of Albino Rats

Abstract

The study aims to clarify the toxic effect of plant hormones, which are widely used in
agriculture. One of these is the plant hormones (indole acetic acid); has been giving the
hormone to rats at 100 ppm salt solution of 0.2 per day after day for a period of forty days
before conception until the fourteenth day or sixteenth or childbirth. Treatment brought
about a marked shortage in the rate of increase in the weight of mice., And a percentage
of the weight of the liver there was a distinct increase in the relative weight of the liver.
As well as the increase in pathological changes and increase the size of the nuclei and
Kupffer cell, as noted widespread and dense clusters of inflammatory cells accompanied
by about the erosion of liver tissue and blood infiltration. Biochemical analyzes showed a
marked decrease of the liver in antioxidant enzymes and an increase in the rate of free
radicals. It was also noted an increase in cases of abortion. The owner of so many birth
defects. It was also noted the lack of body weight in fetuses and increase the absorption
rate of embryos in fetuses of mothers treatment compared to the control group. Showed
microscopic examinations of the liver of mice born in the transaction and the decay in the
presence of hepatic cells and edema, blood vessels and increase the rate of cell death.