A Review on synthesis and biological profiles of some Quinazolines and (4H)-3,1- Quinazolin-4-ones of active substituents and their uses as starting materials in reaction schemes

Abstract

Variety of quinazolines and quinazolinones have been considered as precursors for many novel derivatives depending on type and position of the active substituent(s) they have. A review on the synthesis of some quinazolines and quinazolinones having substituent(s) at 2-, 3-, and 4- positions and their uses as starting materials in the synthesis of novel derivatives have been introduced. Also, their reactions and their dependence on the reaction reagents and/or reaction condition have been discussed. In addition, their role in producing derivatives of valuable biological importance has also been surveyed.